Dr. Brouard's research experience has been oriented towards the rational design and multi-step synthesis of complex natural compounds of marine origin and their analogues to conduct studies of their properties in interaction with biological systems (Institute for Chemical Research-CSIC and University of Pennsylvania).
Currently, he focuses his scientific career on the synthesis of simple molecules inspired by natural products, by using the concepts of biology oriented synthesis (BIOS) and function oriented synthesis (FOS). His major goal is to apply efficient methodologies with few reaction steps, purifications by crystallization and one-pot or multi-component reactions to synthesize compounds with anti-tumour activity (mainly against different types of human leukaemia) generating the least amount of residues possible. Another scientific and social challenge related to his research is the efficient use of those molecules isolated from natural sources as a starting product to generate bioactive compounds. He also collaborates with groups researching on natural products to obtain and characterise secondary metabolites with possible biological or biomedical interest.
Medical chemistry, natural products, bioactive compounds, efficient synthesis, function-oriented synthesis.
- Degree in Chemistry from the Universidad de La Laguna (1994)
- PhD in Chemistry from the Universidad de Sevilla and Instituto de Investigaciones Químicas-CSIC (2000)
- Post-doctorate, Professor Amos B. Smith III University of Pennsylvania (Philadelphia. USA), (2001-2003)
- Senior Scientist at the Institute of Natural Products and Agrobiology-CSIC (2007 - present)
- Contract Doctor I3P (2004-2007)
- Postdoctoral Fellow (University of Pennsylvania 2001-2003)
- Postdoctoral Fellow (IPNA-CSIC 2001)